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Fluconazole action

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  1. MIG Guest

    Fluconazole action


    Fluconazole is an antifungal medication used in the treatment of several fungal infections. Fluconazole widely distributes into body tissues, nails and fluids including saliva, sputum, vaginal secretions. Fluconazole does not undergo first pass metabolism and is excreted mostly in the urine and some in the feces. This drug can also be used in the pediatric population. Mechanism: Fluconazole works by altering the fungal cell membrane. It exerts its fungistatic effect by selectively inhibiting 14-alpha demethylase. This is a cytochrome P-450 enzyme that is necessary for synthesizing ergosterol, which is an important component of the fungal cell membrane. 14-alpha demethylase converts lanosterol to ergosterol. Without ergosterol, 14 alpha-methyl sterols increase which subsequently causes the fungal cell membrane to exhibit increased cellular permeability. propranolol dizziness • Vaginal candidiasis, acute or recurrent; when local therapy is not appropriate. • Chronic oral atrophic candidiasis (denture sore mouth) if dental hygiene or topical treatment are insufficient. • Mucosal candidiasis including oropharyngeal, oesophageal candidiasis, candiduria and chronic mucocutaneous candidiasis. • Candidal balanitis when local therapy is not appropriate. • Dermatomycosis including tinea pedis, tinea corporis, tinea cruris, tinea versicolor and dermal candida infections when systemic therapy is indicated. • Tinea unguinium (onychomycosis) when other agents are not considered appropriate. • Relapse of cryptococcal meningitis in patients with high risk of recurrence.

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    Mechanism of action. Fluconazole is a very selective inhibitor of fungal cytochrome P450 dependent enzyme lanosterol 14-α-demethylase. This enzyme works. tadalafil vs sildenafil Fluconazole capsule is used for the treatment of mucosal candidiasis. Its primary mode of action is the inhibition of fungal cytochrome P-450-mediated 14. Like other imidazole- and triazole-class antifungals, fluconazole inhibits the fungal cytochrome P450 enzyme.

    This is not a list of all drugs or health problems that interact with this medicine (fluconazole tablets). Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (fluconazole tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Fluconazole is used to treat serious fungal or yeast infections, such as vaginal candidiasis, oropharyngeal candidiasis (thrush, oral thrush), esophageal candidiasis (candida esophagitis), other candida infections (including urinary tract infections, peritonitis [inflammation of the lining of abdomen or stomach], and infections that may occur in different parts of the body), or fungal (cryptococcal) meningitis. This medicine works by killing the fungus or yeast, or preventing its growth. Fluconazole is also used to prevent candidiasis in patients having bone marrow transplants who receive cancer or radiation treatment. This medicine is available only with your doctor's prescription.

    Fluconazole action

    Fluconazole C13H12F2N6O - PubChem, Fluconazole 150mg Capsules - Summary of Product Characteristics.

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  3. Medscape - Candidia infection dosing for Diflucan fluconazole, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy.

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    Abr. 2015 - 5 seg - Vídeo enviado por ADictionaryVideo shows what fluconazole means. An antifungal drug used especially against Candida. tamoxifen vs femara Antifungal action Fluconazole exerts its fungistatic effects by inhibiting fungal cytochrome P-450. The spectrum of activity includes Cryptococcus neoformans. Fluconazole is used to treat serious fungal or yeast infections, such as vaginal candidiasis, oropharyngeal candidiasis thrush, oral thrush, esophageal.

     
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