While there is good clinical evidence demonstrating the drug’s efficacy in rheumatoid arthritis and lupus, there are very few studies looking at hydroxychloroquine as a treatment for Sjögren’s. The studies that do exist show mixed results (some show Nonetheless, despite the lack of clinical studies, rheumatologists feel that hydroxychloroquine may have a potential beneficial effect in helping patients with symptoms of fatigue and achiness, which are common complaints in patients with Sjögren’s. Can taking plaquenil cause weight loss Plaquenil side effects with anti depressants Chloroquine side effects sleep Plaquenil hydroxychloroquine is a Disease Modifying Anti-Rheumatic Drug DMARD that is widely used to reduce inflammation pain and swelling in the treatment of many types of arthritis and lupus. Plaquenil is also known as a treatment for malaria, a blood-borne parasite spread by mosquitoes in many tropical and sub-tropical environments. Allergic and psoriasis-like rashes tend to develop within the first few weeks or months of starting Plaquenil. If Plaquenil helps a serious chronic disease such as lupus, it may be taken for years. Some of these long-term users will develop grayish-blue pigmentation on. Pigmentation associated with long-term use of Plaquenil. their shins and forearms. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis. The good news is that hydroxychloroquine targets the immune system without causing an increase in the risk of infection or cancer that can be seen with other immunosuppressant medications. How the drug works is unclear, but recent research has pointed to an inhibitory effect on toll-like receptors that are proteins involved with inflammation. Plaquenil works for what diseases Hydroxychloroquine Plaquenil Side Effects & Dosage for., Plaquenil Use in Autoimmune Diseases Does plaquenil cause low white blood cell countHydroxychloroquine method of action arthritisDoes plaquenil help with inflammationPlaquenil monograph What Conditions does Plaquenil Treat? Malaria caused by the Protozoa Plasmodium Falciparum. Preventive Treatment of Vivax Malaria. malaria prevention. systemic lupus erythematosus. an autoimmune disease. Preventive Treatment of Quartan Malaria. Preventive Treatment of Ovale Malaria. Malaria. What Conditions does Plaquenil Treat? - WebMD. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. It is not known how Plaquenil works but researchers believe that Plaquenil interferes with communication between cells within the immune system. Ultimately, it is thought to block proinflammatory pathways. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. Plaquenil Hydroxychloroquine sulfate is a drug originally used to prevent or treat malaria. Malaria is a serious but rare disease caused by bites from infected mosquitos. Now the drug is used to treat inflammatory diseases. This type of disease occurs when the body's immune system attacks its own healthy tissue.