Antimalarials are usually given as one or two pills, once a day. Side effects include vision changes (blurring, halos around lights and sensitivity to light), headache, dizziness, nausea and vomiting. Individuals taking an antimalarial should have eye examinations periodically. Plaquenil for lupus erythematosus 400 mg hydroxychloroquine Plaquenil and low blood sugar Adults 800 mg 620 mg base followed by 400 mg 310 mg base at 6 hours, 24 hours and 48 hours after the initial dose total 2000 mg hydroxychloroquine sulfate or 1550 mg base. It is known that antimalarial drugs that are helpful in LE are contraindicated in psoriasis 1. This old concept is supported by the recent study of Wolf et al. 11, who demonstrated that hydroxychloroquine induces hyperproliferation and irregular keratinization in cultured skin of psoriatic patients. They're painkillers that ease joint pain and swelling from psoriatic arthritis. But they also can trigger psoriasis flare-ups. Your doctor may lower the dose of these medicines to see if that. The use of Plaquenil may cause a severe flare of psoriasis. Unless you are directed to do so by your doctor, do not take Plaquenil, the most commonly prescribed antimalarial. Plaquenil dosage for psoriatic arthritis Thyroid Disease and Arthritis How They're Connected, Hydroxychloroquine in Psoriasis Is it Really Harmful. Hydroxychloroquine 200 mgAralen retail priceLiquid plaquenilGeneric plaquenil cost I started on plaquenil for Psoriatic Arthritis in 2015. 200mg twice daily. I didn’t feel too bad but a huge bout of stress made my symptoms worse. I then started methotrexate in addition to plaquenil. My rheumatologist suggested once daily Plaquenil and that seemed okay. After a while he said I coujd stop it as he was not sure if it was. Plaquenil User Reviews for Rheumatoid Arthritis at. Drugs & Medications That Can Trigger Psoriasis Flare-Ups. Rheumatoid Arthritis Treatment Options Johns Hopkins.. Plaquenil is a prescription medication approved by the Food and Drug Administration FDA in 1955. Plaquenil is sometimes prescribed to treat inflammation in people with psoriatic arthritis. Plaquenil is also known by its drug name, Hydroxychloroquine. There are several different kinds of medications used to treat psoriatic arthritis PsAtreatments for PsA can be organized into several categories, including Non-Steroidal Anti-Inflammatory Drug NSAID Hydroxychloroquine is a disease-modifying anti-rheumatic drug DMARDregulates the activity of the immune system, which may be overactive in some conditions. Hydroxychloroquine can modify the underlying disease process, rather than simply treating the symptoms.