Chloroquine is an anti-malaria medicine that works by interfering with the growth of parasites in the red blood cells of the human body. Parasites that cause malaria typically enter the body through the bite of a mosquito. Can hydroxychloroquine cause weight loss Does plaquenil effect the brain fog Chloroquine hydrochloride Drug Entry Chloroquine. Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. 4 It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. 17. Chloroquine was granted FDA Approval on 31. ABSTRACT Literature data on the properties of chloroquine phosphate, chloroquine sulfate, and chloroquine hydrochloride related to the Biopharmaceutics Classiﬁcation System BCS are reviewed. The available information indicates that these chloroquine salts can be classiﬁed as highly soluble and highly permeable, i.e. BCS class I. Chloroquine-resistant strains have been reported. Also acts as a tissue amebicide, has antiinflammatory, antihistamine, and antiserotonic properties. Uses. Suppression and treatment of malaria caused by P. malariae, P. ovale, P. vivax, and susceptible forms of P. falciparum, and in the treatment of extraintestinal amebiasis. Chloroquine is used to treat and to prevent malaria. Malaria is common in areas such as Africa, South America, and Southern Asia. Chloroquine hydrochloride properties Chloroquine hydrochloride Semantic Scholar, Biowaiver monographs for immediate release solid oral dosage. Plaquenil side effects kidney Chloroquine is a 4-aminoquinoline with antimalarial, anti-inflammatory, and potential chemosensitization and radiosensitization activities. Although the mechanism is not well understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. Chloroquine C18H26ClN3 - PubChem. CHLOROQUINE HYDROCHLORIDE. Chloroquine Hydrochloride C18H28Cl3N3 ChemSpider. Chloroquine is an anti-malaria medicine that works by interfering with the growth of parasites in the red blood cells of the human body. Parasites that cause malaria typically enter the body through the bite of a mosquito. Co-administration of chloroquine and mefloquine may increase the risk of convulsions. The blood concentrations of chloroquine and desethylchloroquine the major metabolite of chloroquine, which also has antimalarial properties were negatively associated with log antibody titers. Chloroquine Hydrochloride is the hydrochloride salt of chloroquine, a synthetic quinoline with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum.