Chloroquine eye toxicity

Discussion in 'Plaquenil' started by opeg, 03-Mar-2020.

  1. NGT Moderator

    Chloroquine eye toxicity


    Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking chloroquine: Incidence not known Some side effects of chloroquine may occur that usually do not need medical attention.

    Plaquenil medscape Magnesium with hydroxychloroquin

    Hydroxychloroquine, sold under the brand name Plaquenil Sanofi-Aventis, is an antimalarial drug that has gained widespread use in treating various autoimmune diseases, including systemic lupus erythematosus and rheumatoid arthritis. 1 By some estimates, more than 150,000 patients are on long-term therapy with this medication in America alone. 2 Retinal toxicity associated with HCQ use is. Chloroquine and hydroxychloroquine can cause toxic retinopathy due to their binding of melanin in the retinal pigmented epithelium RPE as well as direct toxicity to retinal ganglion cells. Early findings include mottling of the RPE and blunted foveal reflex. As the retinopathy progresses, a bull's-eye maculopathy develops, as seen in these photos. Retinal toxicity from chloroquine CQ and its analogue, hydroxychloroquine HCQ, has been recognized for many years. Chloroquine toxicity remains a problem in many parts of the world, but is seen less frequently in the United States where the drug largely has been replaced by HCQ.

    Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine.

    Chloroquine eye toxicity

    Hydroxychloroquine Plaquenil Toxicity and Recommendations., Bull's-eye maculopathy due to hydroxychloroquine toxicity

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  6. Group I displayed observable chloroquine fundus toxicity, Group II chronic chloroquine use with no observable fundus alterations, and Group III as a normal control group. On SD-OCT 87.5% of Group I showed peripapillary RNFL thinning in at least one quadrant whereas Groups II.

    • Hydroxchloroquine and Chloroquine Toxicity - Eye Lessons.
    • Recommendations on Screening for Chloroquine and..
    • Chloroquine C18H26ClN3 - PubChem.

    Chloroquine and hydroxychloroquine both belong to the quinolone family and share similar clinical indications and side effects, including retinal toxicity. Chloroquine-induced retinal toxicity was first described in 1959 and the retinal toxic effects of hydroxychloroquine were later described in 1967 3, 4. To reduce the incidence of chloroquine and hydroxychloroquine toxicity, health care providers HCP's that prescribe these medications and those that screen for ocular toxicity have developed clear dosing and screening protocols that have reduced the risk of end-stage disease; bull's eye maculopathy and central vision loss Level I. Of course the aim is avoid drug related retinal toxicity, which on ophthalmic examination, appears as the classic Bull’s eye change affecting the macula. Once retinal toxicity from hydroxychloroquine occurs, it is thought that the retinal changes are permanent and the disease can progress even if hydroxychloroquine is stopped for 1 to 3 years.

     
  7. nwcod User

    Also known as: Plaquenil, Quineprox The following information is NOT intended to endorse any particular medication. Lyme Disease new drug cocktail - biaxin, levaquin, diflucan, etc Biaxin and Plaquenil together? What was it like? LymeNet Flash PLAQUENIL FOR BABESIA? - Lyme disease
     
  8. AirLarson Moderator

    This is the most complete list of substances and how they will/may show up in drug screens....include...... Dimethylamphetamine - metabolizes to methamphetamine and amphetamine Dimethylamylamine - false positive for amphetamines Dinintel® - metabolizes to amphetamine Diocalm - may test positive for opiates Diphenhydramine - false positive for phencyclidine Diphenhydramine - false positive for Tricyclic Antidepressants (TCA) Diphenhydramine (Benadryl) - false positive PCP results DMAA (dimethylamylamine) - false positive for amphetamines d-Methamphetamine - HCL may test positive for methamphetamine Doco children's cough syrup - false positive for Opioids Dolobid - false positive for THC, Marijuana Dolophine - may test positive for methadone Dolophine® - contains synthetic opiates Donnagel-PG ® - contains opium/morphine Donnatal - may test positive for barbiturates Donnatal® - contains barbiturates Donnatol (for irritable bowel syndrome) - false positive for barbiturates Dormonocet® - contains benzodiazepines Doxepin - false positive for LSD Doxepin - may test positive for Tricyclic Antidepressants Doxylamine - false positive for phencyclidine, PCP, angel dust Dristan Cold caplets - false positive for Amphetamines Dristan Cough Formula - false positive for Heroin, Opiates, Morphine Dristan Nasal Spray - false positive for Amphetamines Drixoral Cold and Flu - false positive for Amphetamines Dronabinol (Marinol) - shows positives for THC, marijuana Duramorph - positive for opiates Duramorph® - contains morphine Durophet® - Amphetamines E E (slang) - may test positive for methamphetamine and ecstasy Ecstasy (slang) - may test positive for methamphetamine and ecstasy Edecrin - false positive for THC, Marijuana Efavirenz - false positive for THC, Marijuana Efavirenz (Sustiva®) - may test positive for THC Effexor Tablets (venlafaxine hydrochloride) - false positive for PCP Effexor XL - Potential Positive for PCP Efidac/24 - false positive for Amphetamines Efotamine - false positive for LSD Elavil - false positives for opiates for up to three days, LSD, Methadone Elavil - Positive for Tricyclic Antidepressants Eldepryl - false positive for Amphetamines and Ecstasy Elderpryl® - metabolizes to methamphetamine and amphetamine Empirin w/codeine - false positive for Morphine, Opioids Enoxacin - false-positive for opiates Entersan - may test positive for opiates Ephedra - false positives for Amphetamines and Ecstasy Ephedrine - false positive for Amphetamines, Meth, and Ecstasy Ephedrine-based compounds - false positives for Amphetamines and Ecstasy Ephedrol, Ephedra (Ma Haung) - false positive for Amphetamines, Heroin, Opiates Ergostat® - false positive for LSD Esomeprazole - PPIs may test positive for THC Estasule Minus - false positive for Amphetamines, Heroin, Opiates Estazolam - may test positive for Benzodiazepines Etafediabe - false positive for Amphetamines, Meth and Ecstasy Ethylamphetamine - metabolizes to amphetamine Ethylmorphine - may test positive for opiates Eve (slang) - may test positive for amphetamines Excedrin IB - false positives for Marijuana (Cannabis) THC F Factive (Fluoroquinolone) - false positive for opiates Famprofazone - false positive for Amphetamines and Ecstasy Feldene - false positives for THC Fencamine - metabolizes to methamphetamine and amphetamine Fenelylline - false positive for Amphetamines and Ecstasy Fenfluramine - false positive for Ecstasy Fenfluramine (Fen Phen) - may test false positive for amphetamines Fenoprofin - false positive for Marijuana, Amphetamines, Barbiturates Fenproporex - metabolizes to amphetamine Fenproyorex - false positive for Amphetamines and Ecstasy Fentanyl - false positive for LSD (Reference: 47) Finedal® - metabolizes to amphetamine Fioricet - may test positive for Barbiturates Fiorinal - may test positive for Barbiturates Fiorinal known to produce a false positive for phenobarbital Fiorinal w/codeine - false positive for Morphine Floxin (Fluoroquinolone) - false positive for opiates Flunitrazepam - may test positive for Benzodiazepines Fluoroquinolone antibiotics - false positive for opiates Fluoxetine (Prozac) - false positives for amphetamines and LSD Flurazepam - contains benzodiazepines (Reference: 18) Flurbiprofen - false positive for marijuana Fluroquinolones (Levaquin®) - may test false positive for opiates Fluspirilene - may test positive for amphetamines Frisium - may test positive for Benzodiazepines Furfenorex - metabolizes to methamphetamine and amphetamine G Galcodine - may test positive for opiates Galenphol - may test positive for opiates Gamanil - may test positive for Tricyclic Antidepressants Gemifloxacin (Fluoroquinolone) - false positive for opiates Genpril - false positive for THC, Marijuana Gradumet® - contains d-methamphetamine Halcion - Positive for Benzodiazepines (Reference: 52) Haloperidol - false positive for LSD Haltran - false positive for THC, Marijuana Hamantashen - may test positive for opiates. Hydroxychloroquine - I believe this drug causes false. Hydroxychloroquine sulfate and Drug screen positive - from. What Can Cause a False Positive Drug Test - WebMD
     
  9. vodess User

    The pharmacokinetics of three multiple dose regimens of. The pharmacokinetics of three multiple dose regimens of chloroquine implications for malaria chemoprophylaxis. J C Wetsteyn, P J De Vries, B Oosterhuis, and C J Van Boxtel Division of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Center, Amsterdam, The Netherlands.

    Malaria prevention and treatment Nursing Times
     
  10. salmon New Member

    Plaquenil and Ankylosing Spondylitis - Reviews I was diagnosed with lupus in 2004. At the same time I was diagnosed with ankylosing spondylitis. I have been on enbrel for the AS and I've tried plaquenil for the lupus. I do have stomach problems when I start taking the plaquenil. I usually just give up and say it's not worth having a stomach ache!

    Medications Used To Treat Ankylosing Spondylitis And.