I am not shocked about having it just being diagnosed with it. I have seen my rheumatologist for five years and I guess she just thought it was time. Plaquenil for erythema nodosum Hydroxychloroquine reviews sjogren& 39 Plaquenil kidney pain Hydroxychloroquine with lamotrigine with oxycodone Hydroxychloroquine is sometimes combined with methotrexate for additive benefits for signs and symptoms or as part of a regimen of “triple therapy” with methotrexate and sulfasalazine. Mechanism The mechanism of action of antimalarials in the treatment of patients with rheumatoid arthritis is unknown but is thought to involve changes in. Does anyone take methotrexate and hydroxychloroquine and has anyone had problems with hydroxychloroquine. Does anyone know if hydroxychloroquine and methotrexate can cause weight loss. day, been taking for over a year now but although it helps with some of the pain. I have not had problematic side effects from the Plaquenil or MTX, but the steroids caused weight gain and some hair loss besides what was caused by the arthritis. I am still negative for the RA factor, but have suffered with bilateral trochanteric bursitis and pain at the sides of my knees. She tried to put me on it two years ago even before she diagnosed me because she has always suspected lupus. Anyway, I'm scared to death to take plaquenil but I know that I probably should. Weight loss methotrexate and plaquenil Arthritis Medications and Hair Loss Arthritis Foundation, Does anyone take methotrexate and hydroxychloroquine. Chloroquine otcGeneric.plaquenil watsonHydroxychloroquine sulfate and weight gainPlaquenil retinal screeningSeronegativera plaquenil Oct 12, 2016 In multivariable models, more weight loss and a greater risk of weight loss odds ratio 1.73 were evident among those receiving leflunomide compared to those receiving methotrexate. Treatment with prednisone was associated with greater weight gain—an average of 0.072 kg/m2. Which Drugs Cause Weight Gain, Loss in RA? - U. S. Medicine. Plaquenil for RA?" Rheumatoid Arthritis Community - Support Group. Plaquenil vs. Rheumatrex, Trexall Prescription Treatment.. I am not sure what your question is, but Plaquenil is very well tolerated at the dose of 400 mg daily. If you are a very small person your rheumatologist may wish to decrease the daily maintenance dose, but I know that many patients are continued on the 400 mg daily dose for long periods. Dec 18, 2018 Gaining weight while taking methotrexate might be frustrating, but the excess weight can be managed. Make healthy adjustments to your lifestyle to lose weight while on methotrexate. Talk to your doctor before starting a weight loss program while on methotrexate. Does anyone know if hydroxychloroquine and methotrexate can cause weight loss day, been taking for over a year now but although it helps with some of the pain. I have to have steroid.