The reaction can be phototoxic and/or photoallergic. Phototoxic reactions result from direct damage to tissue caused by light activation of the photosensitising agent, whilst photoallergic reactions are a cell-mediated immune response in which the is the light-activated photosensitising agent. Chloroquine cancer clinical trial Starting plaquenil during pregnancy Itching from plaquenil Phototoxic reaction 1. This is the most common type of sun-sensitivity drugreaction. 2. It can occur when the skin is exposed to the sun after certain medications are injected, ingested, or applied to the skin. 3. It may arise within a few hours or up to a few days after the drug is taken. 4. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. A doctor suspects a photosensitivity reaction when a rash appears only in areas exposed to sunlight. A close review of the person's medical history, skin symptoms, any diseases, drugs taken by mouth, or substances applied to the skin such as drugs or cosmetics may help a doctor pinpoint the cause of the photosensitivity reaction. Although some oral photosensitising medications can cause photoallergic reactions, most cause phototoxic reactions. Photoallergic reactions occur less commonly than phototoxic reactions and are mostly caused by photosensitising topical agents. Phototoxic reaction to plaquenil Hydroxychloroquine Sulfate Photosensitivity Reaction Reports., Plaquenil Hydroxychloroquine - Side Effects, Dosage. Plaquenil and effects on growing fetusWhat is in plaquenil Jun 12, 2018 Phototoxic reactions in skin Acute phototoxicity often begins as an exaggerated sunburn reaction with erythema and edema that occurs within minutes to hours of light exposure. Vesicles and bullae may develop with severe reactions. Drug-Induced Photosensitivity Clinical Presentation History.. Photosensitivity Reactions - Skin Disorders - Merck Manuals Consumer.. Hydroxychloroquine and angioedema AAAAI. There are two types of reactions that can increase our sensitivity to the sun. One is called Photoallergic. The other is called a Phototoxic reaction. Both require the combination of medicines and sunlight to occur. Phototoxic reaction happens when the drug is activated by the sun’s rays and the skin is damaged. This often looks like a sunburn. Feb 19, 2020 Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Common side effects of Plaquenil include. nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation, headache, Drug photosensitivity is caused by a phototoxic or photoallergic reaction to certain medications and sunlight. Symptoms include burning, itching, stinging, redness, blisters, and swelling of the affected areas.