My peripheral neuropathy actually went away too, and my rheumy thinks it was a rare, toxic side-effect of the Plaquenil. Get emergency medical help if you have any of these signs of an allergic reaction while taking hydroxychloroquine: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Fatigue is part of malaria, which is the normal use of this medication. What is chloroquine injection Plaquenil and rheumatoid nodules Plaquenil screening form Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Plaquenil hydroxychloroquine sulfate daily for two weeks, then once per week. 5 Quinine is the best-studied drug for nocturnal leg cramps and has been found effective in some studies. Yet quinine is no longer routinely recommended for treatment due to the potential for serious and/or life-threatening side effects. Medscape - Indication-specific dosing for Plaquenil hydroxychloroquine sulfate, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. This is not a complete list of side effects and others may occur. Call your doctor at once if you have a serious side effect such as:muscle weakness, twitching, or uncontrolled movement;loss of balance or coordination;blurred vision, light sensitivity, seeing halos around lights;pale skin, easy bruising or bleeding;confusion, unusual thoughts or behavior; orseizure (convulsions). Less serious side effects of hydroxychloroquine may include:headache, ringing in your ears, spinning sensation;nausea, vomiting, stomach pain;loss of appetite, weight loss;mood changes, feeling nervous or irritable;skin rash or itching; or hair loss. Plaquenil and muscle relaxor Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis, Nighttime Leg Cramps Meds That Hurt, Meds That Help - GoodRx Plaquenil tablets prospect Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Plaquenil hydroxychloroquine sulfate dosing, indications.. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Find patient medical information for Flexeril Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Find information about common, infrequent and rare side effects of Plaquenil Oral. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus.