This medicine is also sometimes given off-label to help the following conditions: Also, let your doctor know if you drink large amounts of alcohol before starting on this medicine. Your doctor will probably want to order frequent tests to check your body's response to chloroquine. Mefloquine chloroquine Plaquenil toxicity guideline Can I take zantac while taking methotrexate and plaquenil? Asked by margmac Updated 13 January 2015 Topics plaquenil, zantac, rheumatoid arthritis, methotrexate, antacid, stomach, contraindication Does Plaquenil Interact with other Medications. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be. Since Chloroquine phosphate tablets are known to concentrate in the liver, it should be used with caution in patients with hepatic disease or alcoholism or in conjunction with known hepatotoxic drugs. Central Nervous System Effects Chloroquine may increase the risk of convulsions in patients with a history of epilepsy. Drug Interactions Let your healthcare provider know if your symptoms either don't improve or worsen while taking this medicine. Keep all appointments with your doctor and laboratory. Drug interaction zantac and chloroquine Drug Interactions With Chloroquine, Plaquenil Oral Interactions with Other Medication Retinal photo plaquenilPlaquenil contraindications espanol Ranitidine is a prescription drug used to treat ulcers of the stomach and intestines and to prevent intestinal ulcers from coming back after they have healed. Ranitidine is also used to treat certain stomach and throat problems such as erosive esophagitis, gastroesophageal reflux disease or GERD, and Zollinger-Ellison syndrome. Ranitidine Zantac Side Effects, Dosages, Treatment, Interactions.. Chloroquine - Prescription Drug Information, Interactions.. Plaquenil Interactions - Antibiotics Home Page. Summary Drug interactions are reported among people who take Zantac and Hydroxychloroquine sulfate together. This study is created by eHealthMe based on reports of 45 people who take Zantac and Hydroxychloroquine sulfate from Food and Drug Administration FDA, and is updated regularly. We would like to show you a description here but the site won’t allow us. This is not a list of all drugs or health problems that interact with chloroquine. Tell your doctor and pharmacist about all of your drugs prescription or OTC, natural products, vitamins and health problems. You must check to make sure that it is safe for you to take chloroquine with all of your drugs and health problems.