Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Malaria tablets chloroquine boots Plaquenil guidelines aao 2016 Adverse reactions plaquenil Skin discoloration is a possible side effect of plaquenil. It can also cause discoloration of your fingernails. Usually it is not serious, but you should let your doctor know about it as soon as you can." Hydroxychloroquine pigmentation can occur within 1 year after starting therapy 4, 12, 13, 17. The skin discoloration has no systemic adverse sequelae. After discontinuation of the drug, the hydroxychloroquine-associated pigmentation slowly fades. Plaquenil Side Effects by Likelihood and Severity INFREQUENT side effects. If experienced, these tend to have a Severe expression. Skin Discoloration; Vomiting; RARE side effects. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Plaquenil side effects skin discoloration Plaquenil and skin discoloration, Hydroxychloroquine-Associated Hyperpigmentation Mimicking. Nifedipine and hydroxy chloroquine Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil Oral Uses, Side Effects, Interactions.. Common and Rare Side Effects for Plaquenil Oral. Plaquenil Side Effects Common, Severe, Long Term -. Jan 15, 2020 Skin hyperpigmentation is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Omniscan, and have Arteriogram A known side effect of using antimalarials long term is dark patches on the skin. The Lupus Encyclopedia Thomas Jr. 2014 says this 'One of the potential long-term side-effects of using anti-malarial medications such as hydroxychloroquine Plaquenil, chloroquine, and quinacrine is the development of dark-colored patches on the skin. Nov 23, 2009 We attribute this to both Plaquenil and Pilates, the latter of which I have now been doing weekly all year, and I also do some of the exercises daily if I find I have joint pain. It always helps. The little while circles on my skin are the only side effect of Plaquenil that I know of.