Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine resistant falciparum malaria treatment Can you drink coffee while on plaquenil Plaquenil and trouble sleeping 200 plaquenil day lupus Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Plaquenil and Depression/Anxiety. I was diagnosed with Sjogren’s a year ago Early Sjogren’s Panel by the doctor I see for Ehlers-Danlos Syndrome. I started at a very low dose- 100mg per day 1/2 of a 200 mg tablet, in addition to a small dose of modafinil I was taking for fatigue, which is my worst symptom. Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil and mood Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus, Plaquenil and Depression/Anxiety - Symptoms and Medical. Hydroxychloroquine prevent miscarriagePlaquenil assistance programChloroquine pretreatment degradationDo you need to stop plaquenil before surgeryChloroquine and brain cancer Mood Changes; Muscle Tremors; Muscle Weakness; Nightmares; Nystagmus, A Condition With Involuntary Eye Movements; Ringing In The Ears; Sensation Of Spinning Or Whirling; Weight Loss Common and Rare Side Effects for Plaquenil Oral. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Ask the Expert Plaquenil and Sjögren’s. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. If it is, just go with it, stick to the plaquenil as after a couple of weeks when your body adjusts to it, most symptoms get better or go away completely. Also, lupus/Connective tissue disease's can also cause depression/anxiety/panic attacks in some people. Yes, Plaquenil suppresses the immune system. Autoimmune disease such as Sjogrens occurs when the body gets "confused" and attacks healthy tissue instead of just attacking the germs. Basically, the immune system is a bit out of control. Plaquenil works by suppressing the immune system.