Common manifestations may include arthralgias and arthritis, Raynaud syndrome, malar and other rashes, pleuritis or pericarditis, renal or central nervous system involvement, and hematologic cytopenias. Diagnosis requires clinical and serologic criteria. Treatment of severe, ongoing, active disease requires corticosteroids and immunosuppressants. Plaquenil 200 mg sanofi Hydroxychloroquine black box warning Chronic cutaneous lupus erythematosus includes discoid lupus erythematosus, lupus erythematosus profundus, chilblain cutaneous lupus, and lupus tumidus. Diagnosis of these diseases requires proper classification of the subtype, through a combination of physical exam, laboratory studies, histology, antibody serology, and occasionally direct immunofluorescence, while ensuring to exclude systemic disease. The treatment of cutaneous lupus erythematosus is centered upon formulating a regimen of topical and systemic therapies designed to reduce disease activity and minimize cosmetic damage. Sun avoidance and sunscreen are important preventative measures proven to minimize cutaneous lupus erythematosus exacerbations. Systemic lupus erythematosus, also known simply as lupus, is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. Symptoms vary between people and may be mild to severe. Common symptoms include painful and swollen joints, fever, chest pain, hair loss, mouth ulcers, swollen lymph nodes, feeling tired, and a red rash which is most commonly on the face. Often there are periods of illness, called flares, and periods of remission during Systemic lupus erythematosus (SLE) is more common among blacks and Asians than whites. Of all cases, 70 to 90% occur in women (usually of child-bearing age). Chronic lupus erythematosus plaquenil Lupus Causes, Risk Factors, Symptoms, Complications., Treatment of Cutaneous Lupus Erythematosus Fundus autofluorescence hydroxychloroquinePlaquenil and sleepiness How Lupus Affects the Lungs About 50% of people with SLE will experience lung involvement during the course of their disease. Five main lung problems occur in lupus pleuritis, acute lupus pneumonitis, chronic fibrotic lupus pneumonitis, pulmonary hypertension, and “shrinking lung” syndrome. How Lupus Affects the Lungs Johns Hopkins Lupus Center. Systemic lupus erythematosus - Wikipedia. Plaquenil Uses, Dosage & Side Effects -. Plaquenil and other anti-malarials are the key to controlling lupus long term, and some lupus patients may be on Plaquenil for the rest of their lives. For this reason, you can think of anti-malarials as a sort of “lupus life insurance.” Unlike chronic cutaneous lupus, subacute cutaneous lupus does not usually cause scarring, but skin discoloration can occur. Acute cutaneous lupus is the most common rash identified with systemic lupus erythematosus. Chronic cutaneous lupus erythematosus. Chronic cutaneous LE accounts for 80% of presentations with cutaneous LE. About 25% of patients with chronic cutaneous LE also have systemic LE. Discoid LE. Discoid LE is the most common form of chronic cutaneous LE.