Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Plaquenil testing protocol Chloroquine sigma autophagy When do you use hydroxychloroquine in rheumatoid arthritis For prolonged treatment of lupus or arthritis, adverse effects include the acute symptoms, plus altered eye pigmentation, acne, anaemia, bleaching of hair, blisters in mouth and eyes, blood disorders, convulsions, vision difficulties, diminished reflexes, emotional changes, excessive coloring of the skin, hearing loss, hives, itching, liver problems or liver failure, loss of hair, muscle paralysis, weakness or atrophy, nightmares, psoriasis, reading difficulties, tinnitus, skin inflammation. One of the most significant side effects of the drug is its possibility of causing eye problems resulting in blurred or decreased vision. The most common issue is damage to the retina. It can impair your color vision or damage the retinal cells particularly in the area right around the central vision. RARE side effects A Change In Vision. Acquired Chromatopsia, A Change In Color Vision. Irritability. Loss Of Muscle Coordination. Low Energy. Mood Changes. Muscle Tremors. Muscle Weakness. Nightmares. Nystagmus, A Condition With Involuntary Eye Movements. Ringing In The Ears. Sensation Of. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Plaquenil ocular side effects Hydroxychloroquine Oral Route Side Effects - Mayo Clinic, What can Hydroxychloroquine Plaquenil do to my eyes? Plaquenil side effects go awayPlaquenil and estrogenDoes plaquenil lower sed rate Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Hydroxychloroquine Oral Uses, Side Effects, Interactions.. Common and Rare Side Effects for Plaquenil Oral. Plaquenil Side Effects on Your Eyes and Vision. Ocular/eye damage is a side effect of Plaquenil seen especially with long term use of medication. Once damage to the eyes are noted, recommendation is to discontinue the medication, as further use can only worsen the ocular damage. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Ocular side effects include pupillary dilation, redness, dryness, blurred vision, and a temporary bluish discoloration to the vision. The Academy of Ophthalmology cautions the use of this drug in individuals with retinitis pigmentosa, macular degeneration, and diabetic retinopathy.