Areas of chloroquine resistant malaria

Discussion in 'Chloroquine 150 Mg' started by mxm2007, 29-Feb-2020.

  1. elers Moderator

    Areas of chloroquine resistant malaria


    Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it.

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    Resistance to chloroquine of malaria strains is known to be associated with a parasite protein named PfCRT, the mutated form of which is able to reduce chloroquine accumulation in the digestive vacuole of the pathogen. QUESTION In India how to treat a child and adult suffering from malaria? ANSWER Chloroquine-resistant malaria has been observed in India and so the first line drug of choice should be an artemisinin-derivative in combination with another drug this group of medications are more generally known as "artemisinin-based combination therapies" or ACTs. Chloroquine resistance is widespread. Chloroquine should not be used for treatment of P. falciparum infections from areas of chloroquine resistance or malaria occurring in patients where chloroquine prophylaxis has failed. Patients infected with a resistant strains of plasmodia should be treated with another antimalarial drug.

    The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead.

    Areas of chloroquine resistant malaria

    The Public Health Impact of Chloroquine Resistance in Africa., Chloroquine-Resistant Malaria

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  6. P. falciparum has developed resistance to nearly all antimalarial drugs currently in use; P. vivax has been found to be resistant to chloroquine and primaquine; and P. Malariae has been reported to be resistant to chloroquine and pyrimethamine in some areas.1-3

    • Drug Resistance – Malaria Site.
    • Aralen chloroquine Malaria Drug Side Effects & Dosage.
    • Chloroquine - an overview ScienceDirect Topics.

    Discuss the most recent information with your doctor before traveling to areas where malaria occurs. Chloroquine is also used to treat infection caused by a different type of parasite ameba by. Since the first reports of chloroquine-resistant falciparum malaria in southeast Asia and South America almost half a century ago, drug-resistant malaria has posed a major problem in malaria control. By the late 1980s, resistance to sulfadoxine-pyrimethamine and to mefloquine was also prevalent on the Thai-Cambodian and Thai-Myanmar Thai-Burmese borders, rendering them established multidrug. P. falciparum or Species Not Identified – Acquired in Areas Without Chloroquine Resistance. For P. falciparum infections acquired in areas without chloroquine-resistant strains, which include Central America west of the Panama Canal, Haiti, and the Dominican Republic, patients can be treated with oral chloroquine. A chloroquine dose of 600 mg base = 1,000 mg salt should be given initially.

     
  7. Arvandor Moderator

    Selected from data included with permission and copyrighted by First Databank, Inc. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus Protecting your eyesight when taking Plaquenil Lupus. Plaquenil Uses, Dosage & Side Effects -
     
  8. temius New Member

    HYDROXYCHLOROQUINE SULFATE TABLETS, USP Hydroxychloroquine sulfate tablets, USP contain 200 mg hydroxychloroquine sulfate, equivalent to 155 mg base, and are for oral administration. Inactive Ingredients colloidal silicon dioxide, crospovidone, hypromellose, lactose monohydrate, magnesium aluminometasilicate, magnesium stearate, polyethylene glycol, povidone, talc, and titanium dioxide