Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Skin splits on fingertips hydroxychloroquine Hydroxychloroquine sulfate high Typical plaquenil maculopathy oct Hydroxychloroquine and cancer risk If you are pregnant or considering becoming pregnant, discuss Plaquenil with your doctors. Though Plaquenil is generally regarded as safe during pregnancy, it is recommended that effective birth control is used throughout the course of Plaquenil treatment and for up to six months after treatment is stopped. Plaquenil is NOT known to start working that fast. It takes anywhere from 4-6 months before the affects of Plaquenil are seen/felt. This is the case with everyone I know that takes it. My rheumy has saidand everything I've read on Plaquenil that Plaquenil NEEDS that amount of time to build in your system before it stats to have beneficial. Aug 26, 2016 How does lupus affect the renal kidney system? Lupus is an autoimmune disease that can affect almost any part of your body, most often your joints, skin, kidneys, heart, lungs, blood, or brain. Your two kidneys are part of your renal system, which also includes two ureters, the bladder, and the urethra. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Does plaquenil have to build up in your system How long does it take for plaquenil to leave your system?, Immune & Autoimmune - Lupus Plaquenil - Can It Work Quickly? Plaquenil cause muscle painHydroxychloroquine and trametinibHydroxychloroquine sulfate for arthritisWho should not take plaquenil Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine Plaquenil. Plaquenil side effects - kidney problems? - Symptoms - Life.. Common and Rare Side Effects for Plaquenil Oral. If you have lupus, ask your rheumatologist for a referral to an ophthalmologist who has up-to-date technology to evaluate your vision for any early problems. Whether the medication is an antimalarial or a corticosteroid, one thing is clear today’s new screening methods, coupled with vigilance on the part of the patient, will go a long way to. Plaquenil and its affect on the immune system. I am so confused and in so much pain. My Rheumy started me on Plaquenil 200 mg 1 x day a few months back. After a few weeks I started to feel some pain/joint relief and more energy. Biliary cirrhosis primary is reported only by a few people who take Plaquenil. We study 57,706 people who have side effects while taking Plaquenil from Food and Drug Administration FDA. Among them, 4 have Biliary cirrhosis primary. Find out below who they are, when they have Biliary cirrhosis primary and more.