Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Hydroxychloroquine and inflexizumab Psoriatic arthritis response to plaquenil Plaquenil infection These findings were suggestive of hydroxychloroquine retinopathy, and the patient was advised to discontinue hydroxychloroquine. At 6-month follow-up, the patient’s visual acuity remained 20/20. Apr 20, 2011 Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Background/Aims Hydroxychloroquine HCQ retinopathy may result in severe and irreversible vision loss, emphasising the importance of screening and early detection. The purpose of this study is to report the novel finding of early optical coherence tomography OCT abnormalities due to HCQ toxicity that may develop in the setting of normal Humphrey visual field HVF testing. Methods Data from. While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula. Oct findings of plaquenil maculopathy Expanded spectral domain-OCT findings in the early detection of., New Plaquenil Guidelines - Natural alternatives for plaquenil Chloroquine and hydroxychloroquine can cause toxic retinopathy due to their binding of melanin in the retinal pigmented epithelium RPE as well as direct toxicity to retinal ganglion cells. Early findings include mottling of the RPE and blunted foveal reflex. As the retinopathy progresses, a bull's-eye maculopathy develops, as seen in these. Bull's-eye maculopathy due to hydroxychloroquine toxicity. Early hydroxychloroquine retinopathy optical coherence.. How to Succeed in Plaquenil Screenings. Report fundus auto fluorescence FAF and spectral-domain optical coherence tomography SD-OCT findings in a patient with early hydroxychloroquine maculopathy. Methods. A 50-year-old man. Request PDF Optical Coherence Tomography Findings in Hydroxychloroquine and Chloroquine-Associated Maculopathy Background Vision loss and maculopathy associated with hydroxychloroquine and. Dence of hydroxychloroquine maculopathy. Table. Clinical, High-Speed Ultra–High-Resolution Optical Coherence Tomography, and Multifocal Electroretinogram Findings From Patients Receiving Hydroxychloroquine Patient No./ Age, y Hydroxychloroquine Dosage, mg/d Diagnosis Treatment, y Symptoms Visual Acuity, OD, OS Color Vision Visual Fields mfERG.