It is a disabling and painful condition which can lead to substantial loss of mobility due to pain and joint destruction. I really liked the Arava, but I I am now on MTX and Simponi now. The disease is also systemic in that it often also affects many extra-articular tissues throughout the body including the skin, blood vessels, heart, lungs, and... I was on the Orencia when I was on the above two you mentioned. Does plaquenil have life long effects Rheumatoid arthritis treatment plaquenil CHICAGO – Combination therapy with leflunomide and hydroxychloroquine met all goals for efficacy, safety, and tolerability among patients with primary Sjögren’s syndrome in a randomized, placebo-controlled pilot study, lending support to evidence suggesting the two drugs have additive benefits. Feb 29, 2008 I had a lot of problems with Methotrexate as well, but I am not having the same issues with arava which I was afraid of. The plaquenil worked wonders for me and I took it solo for about 2 years, but after a while I was starting to have a severe flare that wouldn't let up - so we gave it a push with the Arava. i'm doing quite well with the. Hi Polly, I'm on all 3. I am doing well enough to walk & participate in an exercise class 3 times a week. I get the occasional pain or flare, but I've gotten to a good place by taking all 3 meds. I take plaquenil daily, Arava/leflunomide on Tues & Fri's, and Methotrexate 8 on Sundays. And I go to an opthamologist twice a year, per my Dr's. The doctor then kept me on my plaquenil and added Leflunomide (Arava) to replace the methotrexate. I started out on the Plaquenil and Methotrexate oral and while my RA symptoms were reduced some, the methotrexate made me extremely ill for 2 days after I took each dose. Arava and plaquenil together Anyone used plaquenil and arava which is better? DailyStrength, ARAVA with Humira - Plaquenil pulmonary fibrosisForgot plaquenil muscle weaknessHydroxychloroquine sulfate monitoringPlaquenil and prednisone interactionPlaquenil and vascular system Vaccinations, warfarin, and corticosteroids are among the many products that may react with Arava. This eMedTV resource lists other drugs that may cause interactions with Arava and describes what may happen if these medications are taken together. Arava Drug Interactions - Arthritis Home Page. Hydroxy/ Plaquenil or Leflunomide/ Arava in. - HealthUnlocked. Arava Drug and Medication User Reviews on RxList. So while having RA and MS together is possible, it is not common. Q2. My best friend has been diagnosed with rheumatoid arthritis and suffers with severe pain much of the time. Nov 01, 2018 CHICAGO – Combination therapy with leflunomide and hydroxychloroquine met all goals for efficacy, safety, and tolerability among patients with primary Sjögren’s syndrome in a randomized, placebo-controlled pilot study, lending support to evidence suggesting the two drugs have additive benefits. Rheumatoid arthritis is a chronic disorder for which there is no known cure. Fortunately in the last few years, a shift in strategy toward the earlier institution of disease modifying drugs and the availability of new classes of medications have greatly improved the outcomes that can be expected by most patients.