Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Chloroquine phosphate and prime Plaquenil side effects teeth Plaquenil 200 cost It was then they said this was Scleroderma. I have Scl70 ab and positive ANA. I have mild Raynaud's, arthritis / joint pain 1st symptom, severe fatigue OMG off the charts some days and horrible fluid retention as well as the puffy hands/fingers at times. I was started on 200 mg BID so a 400 mg dose daily. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. I've been very aware over my almost 2 years on Plaquenil that my appetite hasn't increased, and my exercise levels have stayed the same or increased. The retention part I've never really thought about- thanks for bringing it up! I'm not huge on salt as I'm currently on a paleo diet, but I totally agree that upping my water intake is important. Hydroxychloroquine may also be used for purposes not listed in this medication guide. Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil and fluid retention Medications used to treat lupus Lupus Foundation of America, Plaquenil Uses, Dosage & Side Effects - Hydroxychloroquine sulfate 200 mg tab sPlaquenil and lexaproPlaquenil and methotrexate for sjogren's syndrome PLAQUENIL is indicated for the treatment of chronic discoid lupus erythematosus and systemic lupus erythematosus in adults. Rheumatoid Arthritis. PLAQUENIL is indicated for the treatment of acute and chronic rheumatoid arthritis in adults. CONTRAINDICATIONS. Use of PLAQUENIL is contraindicated in patients with known hypersensitivity to 4 PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION. Weight gain while on Plaquenil? lupus. Will you have Fluid retention with Plaquenil - eHealthMe. Want to reduce fluid retention? Try this remedy with barley which has been used in many European countries and even used today. Barley is actually a diuretic which increases the volume of urine and drains fluid from the swollen areas of the body and is also safe to use for pregnant women. Fluid retention, particularly in your lower body; passing low amounts of urine; feeling weak or fatigued ; headache; confusion; nausea; trouble sleeping; muscle cramping; feeling itchy; shortness. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus.