The American College of Rheumatology recommends paracetamol as one of several treatment options for people with arthritis pain of the hip, hand, or knee that does not improve with exercise and weight loss. Paracetamol has relatively little anti-inflammatory activity, unlike other common analgesics such as the nonsteroidal anti-inflammatory drugs (NSAIDs) aspirin, and ibuprofen, but ibuprofen and paracetamol have similar effects in the treatment of headache. Paracetamol can relieve pain in mild arthritis, but has no effect on the underlying inflammation, redness, and swelling of the joint. It has analgesic properties comparable to those of aspirin, while its anti-inflammatory effects are weaker. It is better tolerated than aspirin due to concerns about bleeding with aspirin. Based on a systematic review, paracetamol is recommended by the American Pain Society as a first-line treatment for lower back pain. In contrast, the American College of Physicians found good evidence for NSAIDs but only fair evidence for paracetamol, while other systematic reviews have concluded that evidence for its efficacy is lacking entirely. Etodolac oral tablet is a prescription drug that’s only available as a generic drug. This drug is used to treat short-term pain, as well as long-term joint pain and inflammation in various types of arthritis. Etodolac is approved to treat: Only the extended-release form has been approved to treat children. This medication belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). It isn’t known how this medication works to decrease pain. It may help reduce swelling by lowering levels of prostaglandin, a hormone-like substance that usually causes inflammation. Disclaimer: Our goal is to provide you with the most relevant and current information. 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