While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. "Hydrochloroquine (Plaquenil) has been a blessing for me. Biaxin and plaquenil lyme disease Plaquenil 200mg pret What are similar drugs to plaquenil Hydroxychloroquine treats what autoimmune diseases It doesn’t work. However, there is a variation of the field test called SITA Fast. SITA Fast takes half as long, and even most glaucoma people are realizing it’s just about as good a test. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. It's still not terribly long since you started Plaquenil. Many of us found it a slow process and yes there were times we thought we were winning and then another flare came along. Ideally after 6-9 months you can guage it's effectiveness properly but you will still probably need a good NSAID to help out. I do occasionally experience dry eyes and a little scalp itch but asserting that it's caused by Hydrochloroquine would be anecdotal at best. It took about 5 weeks to take effect but my RA is basically a non factor now. When plaquenil doesn t work Hydroxychloroquine Side-effects, uses, time to work, Treating Lupus with Anti-Malarial Drugs Johns Hopkins. Chloroquine resistant p falciparumChloroquine molecular formula Dec 10, 2012 Med to try when plaquenil doesn't work? on December 10, 2012, AM My understanding, from reading here, is that plaquenil is a good "first line" med for treating autoimmune disorders. Med to try when plaquenil doesn't work? - Sjogren's World. If Plaquenil doesn't work. Lupus Forums at The Lupus Site. Inflammatory Osteoarthritis And Plaquenil. Re Plaquenil not working anymore Lizzy, I took 400mg 200 twice a day for 16-18 months forget exact duration, then was reduced to 200 mg daily. But right from the start, I also needed NSAID's for pain. Does anyone know if hydroxychloroquine and methotrexate can cause weight loss day, been taking for over a year now but although it helps with some of the pain. I have to have steroid. Plaquenil hydroxychloroquine is a medication that has been used for many years to help musculoskeletal symptoms and fatigue in patients with autoimmune conditions such as rheumatoid arthritis, lupus and Sjögren’s.