It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Hydroxychloroquine and lung cancer Plaquenil drug assistance program Chloroquin function in lysosome Chloroquine dreams Plaquenil has helped me on many levels on many days. I think, for me, anyway, the depression and anxiety I often feel is due to the autoimmune issues/sjogrens. I have not noticed an increase in depression/anxiety since being on the plaquenil but that is just me. I have only been on it for about a year now. Bipolar medications address the full spectrum of bipolar symptoms. In reality there are very few true mood stabilizers that address BOTH depression AND mania. These mood stabilizing bipolar drugs tend to be used for long term maintenance in order to prevent mood swings, or at least reduce the frequency. Cimetidine Moderate Avoid concomitant use of hydroxychloroquine and cimetidine as cimetidine may inhibit the metabolism of hydroxychloroquine as observed with the structurally similar chloroquine. However, the mechanism of inhibition of chloroquine metabolism appears to be via CYP inhibition, and hydroxychloroquine is not a known CYP substrate; cimetidine inhibition of hydroxychloroquine metabolism has not been demonstrated. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil and bipolar PLAQUENIL Side Effects, Reviews by Patients -, Medication for Bipolar Depression - The Two Secrets You. Chloroquine ineffective in exoerythrocyticCan you take hydroxychloroquine while pregnantWhat is the cost of plaquenil Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Plaquenil hydroxychloroquine sulfate dose, indications.. The Risk of Retinal Toxicity with Plaquenil. Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. So glad you posted this and I now know I'm not the only one having the crazy reaction to Plaquenil. I have RA and was put on Plaquenil 1 week ago and noticed the extreme moods swings, frustration turning to extreme rage, feeling crazy, then crying over my reactions. I really thought I was going nuts! My Rheumatologist Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.