Metoprolol dosage

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    Metoprolol dosage


    Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Your dose may need to be changed several times in order to find out what works best for you. In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of food you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should first check with your doctor before changing your diet. Many patients who have high blood pressure will not notice any signs of the problem. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well. Switching from immediate-release to extended-release: Use same total daily dose of metoprolol Switching between oral and IV dosage forms: Equivalent beta-blocking effect is achieved in 2.5:1 (oral-to-IV) ratio Dizziness (10%) Headache (10%) Tiredness (10%) Depression (5%) Diarrhea (5%) Pruritus (5%) Bradycardia (9%) Rash (5%) Dyspnea (1-3%) Cold extremities (1%) Constipation (1%) Dyspepsia (1%) Heart failure (1%) Hypotension (1%) Nausea (1%) Flatulence (1%) Heartburn (1%) Xerostomia (1%) Wheezing (1%) Bronchospasm (1%) Anxiety/nervousness Hallusinations Paresthesia Hepatitis Vomiting Arthralgia Male impotence Reversible alopecia Agranulocytosis Dry eyes Worsening of psoriasis Pyronie’s disease Sweating Photosensitivity Taste disturbance Lopressor and Toprol XL only Ischemic heart disease may be exacerbated after abrupt withdrawal Hypersensitivity to catecholamines has been observed during withdrawal Exacerbation of angina and, in some cases, myocardial infarction (MI) may occur after abrupt discontinuance When long-term beta blocker therapy (particularly with ischemic heart disease) is discontinued, dosage should be gradually reduced over 1-2 weeks with careful monitoring If angina worsens markedly or acute coronary insufficiency develops, beta-blocker administration should be promptly reinitiated, at least temporarily (in addition to other measures appropriate for unstable angina) Patients should be warned against interruption or discontinuance of beta-blocker therapy without physician advice Because coronary artery disease (CAD) is common and may be unrecognized, beta-blocker therapy must be discontinued slowly, even in patients treated only for hypertension Use with caution in cerebrovascular insufficiency, CHF, cardiomegaly, myasthenia gravis, hyperthyroidism or thyrotoxicosis (may mask signs or symptoms), liver disease, renal impairment, peripheral vascular disease, psoriasis (may cause exacerbation of psoriasis) May exacerbate bronchospastic disease; monitor closely Beta blockers can cause myocardial depression and may precipitate heart failure and cardiogenic shock Sudden discontinuance can exacerbate angina and lead to MI and ventricular arrhythmias in patients with CAD Worsening cardiac failure may occur during up-titration of metoprolol succinate; if such symptoms occur, increase diuretics and restore clinical stability before advancing the dose of metoprolol succinate; it may be necessary to lower the dose of metoprolol succinate or temporarily discontinue it Bradycardia, including sinus pause, heart block, and cardiac arrest, has been reported; patients with 1° atrioventricular block, sinus node dysfunction, or conduction disorders may be at increased risk Increased risk of stroke after surgery May potentiate hypoglycemia in patients with diabetes mellitus and may mask signs and symptoms Avoid starting high-dose regimen of extended-release metoprolol in patients undergoing noncardiac surgery; use in patients with cardiovascular risk factors is associated with bradycardia, hypotension, stroke, and death Long-term beta blockers should not be routinely withdrawn before major surgery; however, impaired ability of the heart to respond to reflex adrenergic stimuli may augment risks of general anesthesia and surgical procedures Metoprolol loses beta-receptor selectivity at high doses and in poor metabolizers If drug is administered for tachycardia secondary to pheochromocytoma, it should be given in combination with an alpha blocker (which should be started before metoprolol is started) While taking beta blockers, patients with history of severe anaphylactic reaction to variety of allergens may be more reactive to repeated challenge Extended release tablet should not be withdrawn routinely prior to major surgery Hydrochlorothiazide, can cause an idiosyncratic reaction, resulting in acute transient myopia and acute angle-closure glaucoma, which can lead to permanent vision loss if not treated; discontinue hydrochlorothiazide as rapidly as possible if symptoms occur; prompt medical or surgical treatments may need to be considered if intraocular pressure remains uncontrolled; risk factors for developing acute angle-closure glaucoma may include history of sulfonamide or penicillin allergy Caution in patients with history of psychiatric illness; may cause or exacerbate CNS depression Beta-blockers can precipitate or aggravate symptoms of arterial insufficiency in patients with peripheral vascular disease There are no adequate and well-controlled studies in pregnant women Limited data on the use of metoprolol in pregnant women Risk to fetus/mother is unknown; because animal reproduction studies are not always predictive of human response, use if clearly needed Bioavailability: 40-50% (immediate-release) ; 65-77% (extended-release) relative to immediate release Onset: 20 min (IV), when infused over 10 min; onset may be immediate, depending on clinical setting; 1-2 hr (PO) Duration: 3-6 hr (PO); duration is dose-related; 24 hr (ER); 5-8 hr (IV) Peak plasma time: 1.5-2 hr (immediate-release); 3.3 hr (extended-release) Therapeutic range: 35-212 ng/m L The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

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    For people with high blood pressure, the recommended metoprolol tartrate dose is 100 mg once daily or 50 mg twice daily. The suggested starting dosage for the relief of angina symptoms is 50 mg twice a day. For 16 weeks using a cross-overdesipinwhich metoprolol 100 mg daily and metoprolol 200 mg. this as the preferred metoprolol dose for the aged hypertensive. Metoprolol has been used for lowering high blood pressure for over 40 years, and is used for various heart conditions. This drug is not effective.

    Metoprolol is used alone or in combination with other medications to treat high blood pressure. It also is used to prevent angina (chest pain) and to improve survival after a heart attack. Metoprolol also is used in combination with other medications to treat heart failure. Metoprolol is in a class of medications called beta blockers. It works by relaxing blood vessels and slowing heart rate to improve blood flow and decrease blood pressure. High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when you suddenly stop this drug. Some people who have suddenly stopped taking similar drugs have had chest pain, heart attack, and irregular heartbeat. If your doctor decides you should no longer use this drug, he or she may direct you to gradually decrease your dose over 1 to 2 weeks. When gradually stopping this medication, it is recommended that you temporarily limit physical activity to decrease strain on the heart. Get medical help right away if you develop chest pain/tightness/pressure, chest pain spreading to the jaw/neck/arm, unusual sweating, trouble breathing, or fast/irregular heartbeat. Show More This medication is a beta-blocker used to treat chest pain (angina), heart failure, and high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.

    Metoprolol dosage

    Metoprolol tartrate - Drug Summary - PDR. Net, Metoprolol in the aged hypertensive a comparison of two dosage.

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  5. Find patient medical information for Metoprolol Succinate Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

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    Medscape - Hypertension-specific dosing for Lopressor, Toprol XL, Kapspargo Sprinkle metoprolol, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. To deliver metoprolol continuously over the dosage interval. 190 mg of metoprolol succinate equivalent to 25, 50, 100 and 200 mg of metoprolol tartrate, USP. Proper Use. Drug information provided by IBM Micromedex Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

     
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