Although survival rates have improved, over one half of patients with systemic lupus erythematosus have permanent damage in one or more organ systems. Arthritis and cutaneous manifestations are most common, but renal, hematologic and neurologic manifestations contribute largely to morbidity and mortality. Hydroxychloroquine hypokalemia Field of vision test plaquenil Plaquenil liver damage tests Aralen Dosage and Administration The dosage of chloroquine phosphate is often expressed in terms of equivalent chloroquine base. Each 500 mg tablet of Aralen contains the equivalent of 300 mg chloroquine base. Aralen ar´ah-len trademark for a preparation of chloroquine, an antimalarial agent also used as a suppressant of lupus erythematosus. Dose Hydroxychloroquine 5 mg/kg lean body weight. The usual initial dose is 400 mg/day once daily or in divided doses. Dose may be reduced once a clinical response is achieved. Chloroquine 2-3 mg/kg lean body weight; usually not more than 250 mg daily. Indications RA, SLE, discoid lupus erythematosus, palindromic rheumatism Systemic lupus erythematosus has fascinated physicians for almost a century and remains the prototypic autoimmune disease. Treatment approaches emphasize using a combination of drugs to minimize chronic exposure to corticosteroids. Aralen dosage for lupus Aralen, Chloroquine phosphate chloroquine dosing., Aralen definition of Aralen by Medical dictionary Plaquenil side effects liverSide effects of chloroquine In 1956, the U. S. Food and Drug Administration approved HCQ for symptoms of lupus and rheumatoid arthritis, particularly skin inflammation, hair loss, mouth sores, fatigue, and joint pain. Dosing. Hydroxychloroquine is generally prescribed at a daily dose of 6.5 milligrams or less per kilogram of body weight. Drug spotlight on hydroxychloroquine Lupus Foundation of.. RheumaKnowledgy Hydroxychloroquine and Chloroquine Phosphate. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Antimalarials improve lupus by decreasing autoantibody production. This protects against the damaging effects of ultraviolet light from the sun and other sources and improving skin lesions. The two types of antimalarials most often prescribed today for lupus are hydroxychloroquine Plaquenil® and chloroquine Aralen®. Unlike the rapid response seen with steroids, it may take months before antimalarial drugs improve your lupus symptoms. What is the dosage for this Aralen? For acute malaria attacks in adults the initial dose is 1 g followed by an additional 500 mg after 6 to 8 hours, then 500 mg 24 and 48 hours after the first dose. Malaria treatment oral To treat malaria in adults, one dose of oral chloroquine is usually given right away. Then, half the dose is taken six to eight hours later. This is typically followed by half the dose once a day for the next two days. Amebiasis treatment oral To treat amebiasis in adults.