In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Plaquenil antimalarial Plaquenil side effect on eyes Im glad you are not stopping the plaq. Also, after a few weeks of being on it again your stomach issues may go away. This is a common side effect but usually subsides once your body adjusts to the medication. What are the side effects of Plaquenil? The most common side effects are diarrhea, nausea, vomiting, headache, dizziness, skin rash or black spots when you look at things. Most side effects will go away when your body gets used to the medicine. Tell your doctor if you have these side effects. A lower dose may stop them. Tell your doctor if any of the following side effects, as they may be indications of a more serious reaction Headache. Loss of appetite. Dizziness. Nausea. Diarrhea, vomiting, or stomach pain. Skin rash. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Plaquenil side effects go away Drug spotlight on hydroxychloroquine Lupus Foundation of., Lupus Medicines Hydroxychloroquine - Brigham and Women's. Chloroquine ingredientsBupropion and plaquenilHydroxychloroquine generic price Hydroxychloroquine side effects may range from mild to severe, although some side effects may go away with time. Some of the most common side effects of hydroxychloroquine include 3, 4 loss of appetite. diarrhea. headache. nausea. vomiting. stomach pain. shakiness. skin rash. More serious hydroxychloroquine side effects include 3, 4 Hydroxychloroquine Plaquenil Success, Reviews and Side Effects. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Get medical help right away if you have any very serious side effects, including sensitivity to light, vision changes e.g. blurred vision, seeing light flashes/streaks/halos, missing/blacked-out areas of vision, muscle weakness, numbness/tingling/pain of the arms/legs. Aug 29, 2014 This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. The side effect that is of greatest concern is retinal toxicity. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.