It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Natural substitute for chloroquine Gene rdh12 chloroquine retinopathy Uses for plaquenil For prevention of malaria Adults— Standard dosing 400 mg once a week on the same day of each week starting 2 weeks before traveling to an area where malaria occurs, and continued for 4 weeks after leaving the area. Weight-based dosing Dose is based on body weight and must be determined by your doctor. Find patient medical information for Hydroxychloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. For the treatment of systemic lupus erythematosus, patients should take 200 mg to 400 mg of hydroxychloroquine per day as one dose or divided into two separate doses. 1, 2 The recommended hydroxychloroquine dosage for rheumatoid arthritis is 400 mg to 600 mg a day by mouth as a single dose or divided into two separate doses. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Plaquenil 200 mg twice a day Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Hydroxychloroquine Oral Uses, Side Effects, Interactions. Plaquenil and cancerHow to start plaquenilMechanism of hydroxychloroquinePlaquenil and osteoporosisPlaquenil side effects liver Mg PO twice daily plus methotrexate 7.5 to 17.5 mg PO once weekly for 2 years led to an ACR20 in 60% of 58 patients with active disease and a disease duration of at least 6 months. Thirty-three of the 58 patients had an inadequate response to previous methotrexate monotherapy, and 25 patients were methotrexate naive. Plaquenil hydroxychloroquine sulfate dose, indications.. Hydroxychloroquine Plaquenil Success, Reviews and Side Effects. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Diagnosed with Lupus at age 50 after lots of misdiagnosed ailments. First on prednisone and then told steroid was only temp reduce swelling and Plaquenil prescribed and started at 200 mg twice per. Adult dosing ranges from 200 mg or 400 mg per day 6.5mg/kg. In some cases, higher doses can be used. It is recommended one tablet twice daily if taking more than one tablet. One PLAQUENIL tablet contains 200 mg of hydroxychloroquine sulfate, which is equivalent to 155 mg base. Take PLAQUENIL with a meal or a glass of milk. Malaria Prophylaxis. Adults. 400 mg 310 mg base once weekly on the same day of each week starting 2 weeks prior to exposure, and continued for 4 weeks after leaving the endemic area.